J. Xenotransplantation of SCID/Beige mice with U87 cells and GSDCs provided rise to tumors harboring robust mural cell-associated vascular channels. shRNA restrained VM in tumors and subsequently inhibited tumor development. Collectively, all AMG-Tie2-1 the data demonstrate a central role of Flk-1 in the formation of VM in GBM. This study … Continue reading J